PDF Medifocus Guidebook on: Scleroderma

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Of course you want to know — When do I get it? We strive at all times to get it to you on time but here are some indications: Exchanges Fashion, sportswear and shoes only Wrong size? Packaging should be returned in an undamaged condition with the item When does this policy not apply? If the item is: The term scleroderma literally means hardening fibrosis of the skin. The cause of scleroderma is unknown but the disease process is related to a malfunction of the vascular and immune systems.

Researchers believe that the immune system, which protects us against infection and cancer, becomes overactive in patients with scleroderma resulting in the overproduction of collagen connective tissue or "scar" tissue in the body.

Medifocus Guidebook on: Scleroderma

The excess collagen is deposited in the skin and in some cases, in and around the organs and that leads to the characteristic hardening and thickening effect. In some people, scleroderma is localized to the skin while in others, it is systemic with excess collagen building up not only in the skin but in and around various organs such as the esophagus, kidneys, lungs, gastrointestinal tract, heart, and peripheral nervous system. Organ involvement leads to many accompanying complications. Many people with scleroderma experience a plateau where the condition stabilizes, which is then followed by a period of improvement and skin softening.

The most critical period for systemic scleroderma is usually within the first two to five years of onset when there is the highest risk for rapid progression and the development of serious complications. Most cases of scleroderma are seen initially by a dermatologist and, as the condition progresses, patients often are referred to the care of a rheumatologist. It is important for people diagnosed with scleroderma to be examined and followed by their doctor to evaluate the development of other autoimmune conditions or complications.

Fortunately, scleroderma is a rare disease.

Medifocus Guidebook on: Scleroderma - Medifocus. com, Inc. - Google Книги

Data regarding prevalence and incidence varies widely but estimates are that the prevalence number of cases present in the population of scleroderma ranges from cases per million people and the incidence number of people per year diagnosed with scleroderma ranges from 2. This means that scleroderma is believed to affect between approximately 40, to , persons in the United States and some estimates are even higher. The disorder most commonly occurs in women between the ages of 35 and 55, however, men and children can be affected as well.


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  • Women are affected approximately times as frequently as men. There is a slightly increased risk for developing scleroderma among African-Americans. African-Americans are also more likely to develop severe lung complications. Native Indians are also at a higher risk than the general population for development of scleroderma. Specifically, Choctaw Indians in Oklahoma are up to 20 times more likely to get scleroderma than the general population. Scleroderma is not contagious. Genetic factors are thought to be involved in scleroderma since there is a high frequency of other autoimmune disease in families of people with scleroderma.

    However, most people who develop scleroderma do not have relatives with scleroderma and their children do not have a higher risk of developing the disease. If you or a loved one has been diagnosed with scleroderma, it's critical to learn everything you possibly can about this condition so that you can make informed decisions about your treatment.

    "Scleroderma Research: Year in Review" by Tracy M. Frech, M.D.

    That's why we created the Medifocus Guidebook on Scleroderma , a comprehensive page patient Guidebook that contains vital information about scleroderma that you won't find anywhere in a single source. The Medifocus Guidebook on Scleroderma starts out with a detailed overview of the condition and quickly imparts fundamentally important information about scleroderma, including:.

    The secondary complications that may develop in people with systemic scleroderma, including:. Understanding the Standard Treatments Currently, there is no known cure for scleroderma. The primary goals of treatment for people with scleroderma are as follows:. Understanding the standard treatments - and the treatment options - is critical for successfully achieving the goals of treatment for scleroderma.

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    As you read through the section of the Guidebook that focuses on the treatments for scleroderma, you will specifically learn about:. The treatment options that are currently available for the management and treatment of localized scleroderma , including:. The medications that are prescribed for the management and treatment of systemic sclerosis , including:.